Instruction
Registration number:
Trade name: Lactofiltrum
International non-proprietary name:
Dosage form: tablets
Composition:
Active ingredients: 355 mg hydrolyzed lignin, 120 mg lactulose
Additives: natrium croscar-mellose, magnesium stearate.
Description: dark-brown tablets with grey-brown inclusions, plano-cylinder, with facet and hump.
Pharmacotherapeutic group: enterosorbent agent
ATC Code: A07BC
Pharmacological characteristics
Pharmacological effect of the product is presupposed by the properties of its active components – lignin and lactulose.
Hydrolyzed lignin is a natural enterosorbent, consisting of wood hydrolysis products, characterized by high sorbing activity and non-specific desintoxicating effect.
It binds and eliminates pathogenic bacteria and bacterial toxins, medicinal products, poisons, heavy metals salts, alcohol, allergens, and surplus of some metabolites, including bilirubin, cholesterol, carbamide, metabolites, which cause endogenic toxicosis.
Lactofiltrum is not toxic, it is not ingested and entirely eliminated from the intestines within 24 hours.
Lactulose is a synthetic disaccharide, a molecule consists of galactose and fructose residues. Lactulose is not ingested and hydrolyzed in the stomach and intestines upper parts. Lactulose, released from the tablets in the large intestines as a substrate, is fermented by the intestinal normal microflora, thus stimulating bifid bacteria and lactobacilli growth. As a result of lactulose growth, organic acids (lactic acid, acetic acid and formic acid) are generated in the large intestines, and inhibit growth of pathogenic microorganisms, thus reducing nitrogen-containing toxins production. The said process causes osmotic pressure increase in the large intestinal lumen and stimulates peristalsis.
Integrate effect of the product aims at normalization of the large intestinal biocenosis and reduction of endogenic toxic conditions intensity.
Indications
Complex therapy of the intestinal microflora disorders, including due to antibiotic therapy; irritated intestines syndrome, hepatitis and hepatic cirrhosis.
Allergic diseases complex therapy (atopic dermatitis, urticaria fever).
Contraindications
Idiosyncrasy to the product, intestinal obstruction, gastro-intestinal hemorrhages, galactosemia. It is not recommended to administer the product in case of peptic ulcer disease aggravation, or intestinal atony.
Administration and dosage
Administer as necessary, after powdering, wash down with water, 1 hour before meals and administration of other medicinal products, 3 times per day.
Adults and children over 12 – 2-3 tablets at a time.
Children 8-12 – 1-2 tablets, children 3-7 – 1 tablet at a time.
Average treatment duration – 2-3 weeks.
Lengthy administration of the product and repeated courses of treatment shall be undertaken only as prescribed by a physician.
Side effects
Allergic reaction to the product components, in rare cases – meteorism and diarrhea.
Overdose:
Symptoms: constipation, stomach ache.
Treatment: stop administration of the product.
Interaction with other medicinal products:
When administering some other medicinal products, their therapeutic effect may be inhibited.
Special indications
The product may be used as a complex therapy with other medicinal products with complying with their separate administration rules.
Dosage form
10 tablets in a contour cell PVC aluminium lacquered foil package.
10 tablets in a contour cell PVC aluminium lacquered foil package and flexible package in rolls based on aluminium foil for medicinal products.
30 or 60 tablets in a polymer vial.
Each vial, 1, 2,3, 5 or 6 contour cell packages with the instruction shall be placed in a carton package.
Shelf-life
3 years. Do not administer after the expiration date.
Storage conditions
Keep in a dark dry place, maximum temperature 30 îÑ.
Pharmacy purchasing terms
Over the counter.
Manufacturer
ÎÀÎ «STI-MED SORB», Luganskaya St., 53a, Kirov, 610044
Tel.(495) 956-76-84, (8332) 53-60-11.
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